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Dabequine是一苯并喹啉衍生物,结构式为作者等用小鼠和鸡观察了dabequine对疟原虫的作用。药物用蒸馏水稀释后灌胃。以氯喹标准剂量组作对照。结果dabequine的疗效约相当于氯喹的75%:80mg/kg时的效果与氯喹50mg/kg相接近,在100mg/kg时则略超过氯喹50mg/kg。dabequine的化疗
Dabequine is a benzoquinoline derivative of structural formula for the authors observed with mouse and chicken dabequine on Plasmodium effect. Drug diluted with distilled water after gavage. Chloroquine standard dose group for the control. Results The dabequine efficacy was approximately equivalent to 75% of chloroquine: the effect at 80 mg / kg was similar to that of chloroquine at 50 mg / kg and slightly above that of chloroquine at 100 mg / kg. dabequine chemotherapy