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目的:观察中西医结合治疗脾虚湿热型溃疡性结肠炎(UC)的疗效,及其对血小板计数的影响。方法:将94例脾虚湿热型UC患者分为中西医结合治疗组(ZX组)33例、中药组(Z组)30例、西药组(X组)31例。ZX组采用口服自拟敛溃汤和柳氮磺胺吡啶片,并配合静脉滴注丹参注射液,Z组采用口服敛溃汤,X组采用口服柳氮磺胺吡啶片,3组均治疗8周后观察临床症状、肠镜下黏膜情况以及血小板计数变化情况。结果:8周后临床疗效与降低血小板计数方面ZX组均优于Z组与X组。结论:中西医结合治疗UC疗效显著,降低血小板水平可能是其治疗UC的机制之一。
Objective: To observe the curative effect of integrated traditional Chinese and western medicine on spleen-damp-heat type ulcerative colitis (UC) and its effect on platelet count. Methods: A total of 94 patients with spleen-heat damp-heat syndrome were divided into three groups: ZX group (33 cases), Chinese medicine group (Z group) and western medicine group (X group). ZX group was treated with orally administered self-contained crushing soup and sulfasalazine tablets, and with intravenous injection of Salvia miltiorrhiza injection, Z group oral convergence curd soup, X group oral sulfasalazine tablets, three groups were treated for 8 weeks Observation of clinical symptoms, colonoscopic mucosa and platelet count changes. Results: After 8 weeks clinical efficacy and reduce platelet count ZX group were better than the Z group and X group. Conclusion: The treatment of UC with traditional Chinese and western medicine has obvious curative effect. Reducing the level of platelet may be one of its mechanisms in the treatment of UC.