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80%晚期肝硬变或暴发性肝衰竭的病人血液尿素浓度增高。其肾功不良有两种类型,第一种表现是功能性肾功衰竭,肾小球滤过率下降,排水负荷能力降低,血液尿素及肌酸浓度增高。尿量减少并且浓缩(尿:血浆渗透性比率超过1:1.10),有低钠,这说明肾小管功能还存在。从肾脏活检标本可见正常肾小球,当这种患病的肾脏一旦被移植给肝脏正常的接受者时,肾脏功能仍可恢复,这两点都说明此种肾脏损害是功能性的。晚期肝硬变病人经过正常部位的肝脏移植后,肾脏功能可得到改善。肾功衰竭的第二种表现是以肾小管损害为特征。有低渗性尿;尿钠浓度
80% of patients with advanced cirrhosis or fulminant hepatic failure have elevated blood urea concentrations. There are two types of renal dysfunction, the first performance is functional renal failure, decreased glomerular filtration rate, reduced drainage load capacity, blood urea and creatine concentrations increased. Decreased urine output and concentration (urine: plasma permeability ratio of more than 1: 1.10), there is low sodium, suggesting that renal tubular function still exists. Normal glomerulus can be seen from a biopsy specimen of the kidney, and when the diseased kidney is transplanted to a normal recipient in the liver, the renal function can still be restored, both of which indicate that such kidney damage is functional. Late liver cirrhosis patients after normal liver transplantation, renal function can be improved. The second manifestation of renal failure is characterized by tubular damage. Has hypotonic urine; urine sodium concentration