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目的 探讨血液凝固系统有关因子 t- PA、β- TG、TM和 TSP在急性脑血管病发病中的意义。方法 应用 Diagnostica Stago公司试剂盒 ,EL ISA法测定上述因子血清中含量。结果 急性脑梗死和脑出血患者血清中t- PA含量较对照组增高 (P<0 .0 5 ) ,脑出血患者较脑梗死患者有升高倾向 ;β- TG、TM和 TSP含量急性脑梗死和脑出血患者与对照组比无明显差异。结论 t- PA血清含量在急性脑梗死和脑出血患者中均增高 ,两者有否差异及β- TG、TM和 TSP在脑血管病中的作用有待进一步研究。
Objective To investigate the significance of t-PA, β-TG, TM and TSP in the pathogenesis of acute cerebrovascular disease in blood coagulation system. Methods Serum levels of the above factors were determined by ELISA kit using Diagnostica Stago kit. Results The serum levels of t-PA in patients with acute cerebral infarction and cerebral hemorrhage were significantly higher than those in the control group (P <0.05). Patients with cerebral hemorrhage had a tendency to increase in patients with cerebral infarction. The levels of β-TG, TM and TSP in acute cerebral infarction And cerebral hemorrhage patients with no significant difference compared with the control group. Conclusion The serum levels of t-PA in both acute cerebral infarction and intracerebral hemorrhage patients are increased, the difference between them and the role of β-TG, TM and TSP in cerebrovascular disease need further study.