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结缔组织生长因子(connectivetissuegrowthfactor,CTGF)是肺纤维化(PF)发病过程中细胞因子网络中的关键因子之一。本研究拟观察CTGF及其相关因子在博莱霉素(BLM)致大鼠肺纤维化肺组织中的表达状况,探讨它们在肺纤维化形成中的作用。材料与方法 (1)实验动物及分组:Wistar大鼠4
Connective tissue growth factor (connective tissue growth factor, CTGF) is one of the key factors in the cytokine network during the pathogenesis of pulmonary fibrosis (PF). This study was to observe the expression of CTGF and its related factors in pulmonary fibrosis induced by bleomycin (BLM) in rats and their roles in pulmonary fibrosis. Materials and Methods (1) Experimental animals and groups: Wistar rats 4