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目的研究0．1 Hz极低频交变磁场全身暴露对金黄地鼠眼视网膜内多巴胺含量的影响。方法36只成熟雄性金黄地鼠随机分为4组,每组9只,1组为对照组,另3组分别全身间断暴露于50、 75、100 mT交变磁场7 d,每天暴露8 h,然后测定视网膜内神经递质多巴胺含量。结果场强在50 mT 时,地鼠视网膜内多巴胺含量变化无统计学意义(P>0．05),而在75、100 mT时地鼠视网膜内多巴胺含量增加有统计学意义(P<0．01)。100 mT比75 mT时地鼠视网膜内多巴胺含量增加有统计学意义(P< 0．05)。结论全身暴露磁场强度到达一定水平时可刺激金黄地鼠视网膜内多巴胺的合成和分泌,强度越强作用越明显,若长期的强磁场暴露将可能因视网膜内多巴胺含量的变化而影响视网膜的功能。
Objective To study the effect of 0.1 Hz very low frequency alternating magnetic field on the dopamine content in the retina of golden hamster. Methods Thirty-six male Hamsters were randomly divided into 4 groups (9 rats in each group). One group was control group. The other three groups were exposed intermittently for 50 days at 75,100 mT alternating magnetic field for 7 days, The retinal neurotransmitter dopamine content was then determined. Results At 50 mT, there was no significant difference in the dopamine content in the retina of the gophers (P> 0.05). However, the dopamine content in the retina of the gopher at 75,100 mT increased significantly (P <0. 01). The dopamine content in retina of 100 mT was significantly higher than that of 75 mT (P <0.05). Conclusion The whole body exposed magnetic field intensity can stimulate the synthesis and secretion of dopamine in the retina of golden hamster. The stronger the intensity, the more obvious the effect. If the long-term strong magnetic field exposure will affect the retinal function due to the change of the dopamine content in the retina.