目的探讨脑脊液置换治疗丘脑出血破入脑室的临床疗效;方法设治疗组36例,对照组32例,两组入院后均行常规治疗,治疗组加脑脊液置换术并行鞘内注射地塞米松,每天或隔天一次,共置换2～7次;结果:治疗组的有效率在94.44%,对照组在71.18%,经统计学处理有显著性差异(P<0.01);用GCS评分对治疗前后进行比较,也具有显著性差异(P<0.01);对比了甘露醇的使用时间、头痛的缓解程度、脑膜刺激征的消失时间及住院天数均具有显著性差异(P<0.01);结论用脑脊液置换术治疗丘脑出血破入脑室能极早减轻头痛,缓解临床症状,缩短住院时间,有效地避免脑积水或脑血管痉挛的发生。 Objective To investigate the clinical efficacy of cerebrospinal fluid replacement for treatment of thalamic hemorrhage in the ventricle. Methods Thirty-six patients in the treatment group and 32 in the control group were enrolled in the study. All patients underwent conventional therapy after admission. Patients in the treatment group received intrathecal dexamethasone replacement with cerebrospinal fluid replacement Or another day, a total of 2 to 7 times permutation; Results: The effective rate of the treatment group was 94.44%, the control group was 71.18%, statistically significant (P <0.01); GCS score before and after treatment (P <0.01). The time of mannitol administration, the degree of headache relief, the time of disappearance of meningeal irritation and the days of hospitalization were all significantly different (P <0.01) .Conclusion The use of cerebrospinal fluid replacement The treatment of thalamic hemorrhage broken into the ventricle can reduce headache, alleviate clinical symptoms, shorten the hospital stay, effectively prevent the occurrence of hydrocephalus or cerebral vasospasm.