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目的观察复方斑蝥胶囊联合化疗治疗老年晚期胃癌的疗效。方法 100例老年晚期胃癌患者为研究对象,随机分为观察组和对照组,各50例。两组均给予化疗治疗,观察组在此基础上给予复方斑蝥胶囊治疗。比较两组患者的短期疗效、生活质量及不良反应。结果观察组患者的短期治疗有效率为48.00%,高于对照组的28.00%,差异具有统计学意义(P<0.05)。观察组患者生活质量有效率为62.00%,高于对照组的42.00%,差异具有统计学意义(P<0.05)。观察组白细胞减少例数7例少于对照组的16例,差异具有统计学意义(P<0.05);两组其他不良反应发生情况比较差异无统计学意义(P>0.05)。结论复方斑蝥胶囊联合化疗治疗老年晚期胃癌患者的疗效显著,具有较高的临床应用价值。
Objective To observe the curative effect of compound cantharidin capsule and chemotherapy on elderly patients with advanced gastric cancer. Methods 100 cases of elderly patients with advanced gastric cancer were randomly divided into observation group and control group, 50 cases each. Both groups were given chemotherapy, the observation group on the basis of Compound Cantharidin Capsule treatment. Short-term efficacy, quality of life and adverse reactions in both groups were compared. Results The short-term effective rate of the observation group was 48.00%, which was higher than that of the control group (28.00%), the difference was statistically significant (P <0.05). The effective rate of quality of life in the observation group was 62.00%, which was higher than that in the control group (42.00%), the difference was statistically significant (P <0.05). There were 7 cases of leukopenia in the observation group and 16 cases in the control group, the difference was statistically significant (P <0.05). There was no significant difference in other adverse reactions between the two groups (P> 0.05). Conclusion Compound canthari capsule combined with chemotherapy in the treatment of elderly patients with advanced gastric cancer has a significant effect, with high clinical value.