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目的探讨早期液体治疗对急性胰腺炎预后的影响。方法对2000年1月至2008年9月174例急性胰腺炎患者进行液体治疗后回顾性分析,按时间先后顺序分为两组:2000年1月至2002年8月(A组)病例45例给予液体正平衡治疗。2002年9月至2008年9月(B组)病例129例给予液体负平衡治疗。结果A组40例中有12例发展成重症胰腺炎,死亡4例。另外5例为入院时已诊断为重症胰腺炎,死亡2例。B组109例中有14例发展成重症胰腺炎,无死亡患者。另外20例为入院时已诊断为重症胰腺炎,死亡3例。结论对急性胰腺炎行早期液体治疗,尤其是行液体负平衡治疗能有效地预防急性胰腺炎病情进一步加重,即使对重症胰腺炎也能减少并发症,降低死亡率,改善预后。
Objective To investigate the effect of early liquid therapy on the prognosis of acute pancreatitis. Methods A retrospective analysis was performed on 174 patients with acute pancreatitis from January 2000 to September 2008 after liquid therapy. The patients were divided into two groups according to the time sequence: January 2000 to August 2002 (group A), 45 cases Give liquid a balanced treatment. From September 2002 to September 2008 (group B) 129 cases were given liquid negative balance therapy. Results A group of 40 cases of 12 cases developed into severe pancreatitis, died in 4 cases. The other 5 cases were diagnosed with severe pancreatitis at hospital admission, 2 died. B group of 109 cases, 14 cases developed severe pancreatitis, no deaths. The other 20 cases were diagnosed with severe pancreatitis on admission, 3 patients died. Conclusion Early liquid therapy for acute pancreatitis, especially liquid negative balance therapy can effectively prevent acute pancreatitis further aggravate the disease, even for severe pancreatitis can reduce complications, reduce mortality and improve prognosis.