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目的观察中西药联合治疗帕金森合并认知功能患者的效果。方法将帕金森合并认知功能障碍的患者98例随机分为试验组和对照组各49例。对照组均予常规治疗,试验组在对照组治疗的基础上给予针灸及中药治疗。比较2组患者治疗前、治疗后蒙特利尔认知评估量表(Mo CA)、简易精神状态量表(MMSE)评分。结果治疗前2组Mo CA及MMSE评分比较差异无统计学意义(P>0.05)。治疗后试验组Mo CA评分高于治疗前,对照组Mo CA评分低于治疗前,差异均有统计学意义(P<0.05);且治疗后试验组Mo CA评分高于对照组,差异有统计学意义(P<0.05)。治疗后2组MMSE评分均高于治疗前,且试验组高于对照组,差异均有统计学意义(P<0.05)。结论中西药联合治疗帕金森合并认知功能障碍患者,可明显改善其认知功能,值得推广应用。
Objective To observe the effect of combined treatment of traditional Chinese and western medicine on patients with Parkinson’s disease and cognitive function. Methods A total of 98 patients with Parkinson’s disease complicated with cognitive impairment were randomly divided into experimental group and control group with 49 cases each. The control group were given routine treatment. The experimental group was given acupuncture and Chinese herbs on the basis of the control group. The scores of MoCA and MMSE before and after treatment in two groups were compared. Results There was no significant difference in MoCA and MMSE score between the two groups before treatment (P> 0.05). After treatment, the MoCA score in the experimental group was higher than that before treatment, while the MoCA score in the control group was lower than that before treatment (P <0.05); and after the treatment, the MoCA score in the experimental group was higher than that in the control group Significance (P <0.05). MMSE scores of two groups after treatment were higher than before treatment, and the experimental group than the control group, the difference was statistically significant (P <0.05). Conclusions The combined treatment of traditional Chinese and western medicine in patients with Parkinson’s disease combined with cognitive impairment can significantly improve their cognitive function, which is worth popularizing and applying.