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目的:探讨异位妊娠保守治疗的方法,提高临床治疗水平。方法:对我院收治的32例异位妊娠患者的临床资料进行回顾性分析,均给予保守药物治疗,所用药物为甲氨蝶呤(MTX)和米非司酮,观察临床治疗效果。结果:①观察组14例患者成功13例,失败1例,成功率为92.8%;对照组18例患者成功16例,失败2例,成功率为88.9%。两组患者成功率比较差异不大(P>0.05)。②两组患者包块消失及β-HCG值正常水平时间比较差异显著(P<0.01)。③观察组患者出现恶心2例,对照组患者出现恶心2例,WBC下降1例。结论:对于包括未破裂患者可酌情采用保守药物治疗,甲氨蝶呤(MTX)和米非司酮联合治疗效果较为理想,且临床安全性较高,值得推广应用。
Objective: To explore the conservative treatment of ectopic pregnancy and improve the level of clinical treatment. Methods: The clinical data of 32 patients with ectopic pregnancy admitted to our hospital were retrospectively analyzed. All patients were given conservative drug therapy. The drugs used were methotrexate (MTX) and mifepristone, and the clinical effects were observed. Results: ① In the observation group, 13 cases were successful in 13 cases, one case failed and the success rate was 92.8%. In the control group, 18 cases succeeded in 16 cases and failed in 2 cases, with a success rate of 88.9%. There was no significant difference in success rate between the two groups (P> 0.05). ② There was significant difference between the two groups in the disappearance of mass and the normal level of β-HCG (P <0.01). In the observation group, nausea occurred in 2 patients, in the control group, nausea occurred in 2 patients and WBC decreased in 1 patient. CONCLUSIONS: The combination of methotrexate (MTX) and mifepristone is an ideal treatment for patients with unruptured tuberculosis, including conservative treatment. The clinical safety is high and it is worth popularizing and applying.