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目的观察桂枝茯苓丸联合米非司酮治疗子宫肌瘤的临床疗效。方法选取2013年6月至2015年12月我院收治的54例子宫肌瘤患者作为研究对象,按照随机数字法分为对照组和治疗组,各27例。对照组采用米非司酮治疗,治疗组在对照组治疗方法的基础上联合桂枝茯苓丸治疗。治疗3月后统计疗效。结果治疗组总有效率为88.89%,显著高于对照组的70.37%,2组比较差异有统计学意义(P<0.05)。与同组治疗前比较,2组子宫及子宫肌瘤体积均显著缩小,且雌激素和孕激素水平均显著降低,血红蛋白含量均显著升高,差异均有统计学意义(P<0.05);治疗后,治疗组子宫及子宫肌瘤体积、雌激素和孕激素水平均显著小于对照组,血红蛋白含量显著高于对照组,差异均有统计学意义(P<0.05)。结论桂枝茯苓丸联合米非司酮治疗子宫肌瘤临床疗效满意,可显著缩小子宫肌瘤体积,降低雌激素和孕激素水平,同时升高血红蛋白含量。
Objective To observe the curative effect of Guizhi Fuling pill combined with mifepristone on uterine fibroids. Methods 54 cases of uterine leiomyoma admitted from June 2013 to December 2015 in our hospital were selected as the research object and divided into control group and treatment group according to random number method, with 27 cases in each group. The control group with mifepristone treatment, the treatment group in the control group based on the treatment of Guizhi Fuling pill treatment. After 3 months of treatment, the statistical effect was observed. Results The total effective rate in the treatment group was 88.89%, which was significantly higher than that in the control group (70.37%). There was significant difference between the two groups (P <0.05). Compared with the same group before treatment, the volume of uterus and uterine fibroids in both groups were significantly reduced, and the estrogen and progesterone levels were significantly lower, hemoglobin content were significantly increased, the difference was statistically significant (P <0.05); treatment After treatment, the volume of uterine and uterine fibroids, the levels of estrogen and progesterone in the treatment group were significantly less than those in the control group, and the hemoglobin content was significantly higher in the treatment group than in the control group (P <0.05). Conclusion Guizhi Fuling pill combined with mifepristone treatment of uterine fibroids clinical efficacy is satisfactory, can significantly reduce the size of uterine fibroids, reduce estrogen and progesterone levels, while increasing hemoglobin content.