本文采用免疫比浊法测定了27例小儿病毒性脑炎和化脓性脑膜炎脑脊液α_1—酸性糖蛋白(α_1—AG)和前白蛋白(PA)的含量。结果显示化脑组急性期脑脊液α_1—AG含量明显升高,PA含量显著下降,与病脑组及对照组相比差异有显著性;恢复期除1例化脑患儿脑脊液α_1—AG持续上升,PA持续下降,经治疗无效死亡外,余均恢复正常。表明脑脊液α_1—AG和PA测定不仅可以作为病脑与化脑鉴别诊断的指标,而且对预后判断和疗效观察有重要参考价值。 In this study, the immunoturbidimetric method was used to determine the contents of α 1 -AG (α 1-AG) and prealbumin (PA) in cerebrospinal fluid of 27 children with viral encephalitis and purulent meningitis. The results showed that the content of α 1 -AG in cerebrospinal fluid and the content of PA in acute cerebral ischemia group were significantly decreased, which were significantly different from those in the control group and the control group , PA continued to decline, the treatment died, the rest were normal. The results indicate that the determination of cerebrospinal fluid α_1-AG and PA not only can be used as an index for the differential diagnosis of brain and brain, but also has an important reference value for judging the prognosis and observing the curative effect.