经外耳道-中耳鼓室途径直接用药到内耳不是新的概念。1990年开展的经鼓室注射庆大霉素治疗梅尼埃病,使鼓室用药治疗内耳疾病技术在近年快速发展。鼓室用药有优于胃肠外或静脉给药的优点:靶向性好、用药量少而局部药物浓度高。除鼓室注射利多卡因治疗耳鸣外,目前鼓室使用的药物 Direct administration to the inner ear via the external auditory canal-middle ear tympanum is not a new concept. In 1990, the tympanic injection of gentamycin in the treatment of Meniere’s disease, tympanic treatment of inner ear disease technology in recent years rapid development. Tympanic medication has advantages over parenteral or intravenous administration: good targeting, low dosage, and high local drug concentration. In addition to tympanic injection of lidocaine for tinnitus, the current tympanic drugs used