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目的：探讨非胰岛素依赖性糖尿病（ＮＩＤＤＭ）患者发生脑梗塞的血脂预示因素。方法：对正常人组、非ＮＩＤＤＭ脑梗塞组、ＮＩＤＤＭ无脑梗塞组、ＮＩＤＤＭ脑梗塞组进行血糖、糖化血红蛋白Ａ１ｃ、血脂、纤维蛋白原的测定，并加以比较。结果：甘油三酯、载脂蛋白Ｂ、高密度脂蛋白胆固醇（ＨＤＬ－Ｃ）在ＮＩＤＤＭ脑梗塞组与ＮＩＤＤＭ无脑梗塞组间有显著差异，低密度脂蛋白胆固醇（ＬＤＬ－Ｃ）各组间无显著差异，其余指标ＮＩＤＤＭ脑梗塞组与非ＮＩＤＤＭ脑梗塞组无显著差别。结论：ＮＩＤＤＭ患者是发生脑梗塞的高危人群，其中甘油三酯、载脂蛋白－Ｂ显著升高，ＨＤＬ－Ｃ显著降低，可能是预示ＮＩＤＤＭ患者发生脑梗塞的重要预示因素，总胆固醇、载脂蛋白Ａ１、脂蛋白（ａ）、纤维蛋白原可能仅是次要危险因素。
Objective: To investigate the predictive factors of blood lipids in patients with cerebral infarction in non-insulin dependent diabetes mellitus (NIDDM). Methods: The blood glucose, glycosylated hemoglobin A1c, blood lipid and fibrinogen were measured and compared in normal group, non-NIDDM cerebral infarction group, NIDDM non-cerebral infarction group and NIDDM cerebral infarction group. Results: There was significant difference between triglyceride, apolipoprotein B and high density lipoprotein cholesterol (HDL-C) between NIDDM cerebral infarction group and NIDDM non-cerebral infarction group. Low density lipoprotein cholesterol (LDL-C) No significant difference between the other indicators NIDDM cerebral infarction group and non-NIDDM cerebral infarction group no significant difference. Conclusion: Patients with NIDDM are high risk of developing cerebral infarction. Triglyceride, apolipoprotein-B and HDL-C are significantly decreased, which may be an important predictor of cerebral infarction in patients with NIDDM. Total cholesterol, Protein A1, lipoprotein (a), fibrinogen may be only secondary risk factors.