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t(9;22)是存在于90%以上慢性粒细胞白血病(CML)患者中的一个特征性遗传学标记[1],该易位主要导致bcr/ablP210转录本形成,但近年来陆续有文献报道在CML中也可导致bcr/ablP190转录本形成。为此,我们建立了实时定量PCR(realtimequantitativePCR,RQ PCR)法并初步对20例CML和2例t(9;
t (9; 22) is a characteristic genetic marker present in more than 90% of patients with chronic myeloid leukemia (CML) [1]. This translocation mainly results in the formation of bcr / ablP210 transcripts, but in recent years, It has also been reported that in CML bcr / ablP190 transcript formation can also result. To this end, we established a real-time quantitative PCR (RQ PCR) method and preliminary analysis of 20 cases of CML and 2 cases of t (9;