肺部超声联合氧合指数检测诊断重症肺炎患者病情严重程度及预后的效果研究

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目的 探讨胸部超声联合氧合指数(oxygenation index, OI)在诊断重症肺炎病情严重程度的价值.方法 选取2016年1月—2017年12月在百色市人民医院治疗的重症肺炎患者68例(重症组),同时选取普通肺炎患者70例作为对照(普通组),比较两组胸片超声评分、OI、临床肺部感染评分(clinical pulmonary infection score CPIS)评分和急性生理与慢性健康状况评分系统Ⅱ(APACHEⅡ)评分差异.结果 重症组肺部超声评分、CPIS评分和APACHEⅡ评分分别为(20.03±3.28)分、(8.10±1.04)分和(24.20±3.29)分,明显高于普通组,而OI为(102.20±41.20),明显低于普通组(P<0.05);重症组肺部超声评分与CPIS评分、APACHEⅡ呈正相关(r=0.533和0.510,P<0.05),OI与CPIS评分、APPACHEⅡ呈负相关(r=-0.412和-0.467,P<0.05);重症组死亡患者肺部超声评分为(24.11±3.20)分,明显高于存活患者(P<0.05),而OI为(90.02±19.28),明显低于存活患者(P<0.05);肺部超声评分和OI预测重症肺炎患者死亡的ROC曲线下面积分别为0.819和0.762,P<0.05,截断值分别为22分和102.95,灵敏度分别为75.00%和73.30%,特异度分别为77.27%和70.05%;肺部超声评分联合OI预测重症肺炎患者死亡的ROC曲线下面积为0.910,P<0.05,灵敏度为80.10%,特异度为78.50%.结论 肺部超声联合氧合指数评估重症肺炎患者病情及预后有较好的价值,值得临床使用.“,”Objective To explore the value of chest ultrasound combined with oxygenation index (OI) in the diagnosis of the severity and prognosis of severe pneumonia. Methods 68 in-patients with severe pneumonia (severe group) and 70 cases of common pneumonia (ordinary group), underwent lung ultrasound score, Samples of arterial blood were col?lected to test the oxygenation Index (OI). Clinical pulmonary infection score (CPIS) and acute physiological and chronic health status system II (APACHE II) score were calculated. Results The lung ultrasound score, CPIS score, and APACHE II score of the severe group were (20.03±3.28), (8.10±1.04) and (24.20±3.29) respectively , all significantly higher than those of the ordinary group [(5.83±1.12), (4.02±1.01), and (12.01±1.93) respectively, all P=0.000].The OI of the severe group was (102.20±41.20), significantly lower than that of the ordinary group [ (320.03±21.02), P<0.05]. The lung ultrasound score of the dead cases in the severe group was (24.11±3.20) , significantly higher than that of the surviving patients (P<0.05), while the OI of the dead cases in the severe group was (90.02±19.28), significantly lower than that of the surviving patients (P<0.05); The areas under the ROC curve of lung ultrasound score and OI for pre?dicting the mortality of the severe pneumonia patients were 0.819 and 0.762 respectively (P<0.05), and the cut-off val?ues were 22 and 102.95 respectively, the sensitivity was 75% and 73.30% respectively, and the specificity was 77.27% and 70.05% respectively; The area under the ROC curve of pulmonary ultrasound score combined with OI in predicting the death of severe pneumonia patients was 0.910 (P < 0.05), the sensitivity was 80.10% and the specificity was 78.50%. Conclusion Lung ultrasound combined with oxygenation index is of great value in evaluating the severity and prognosis of severe pneumonia, and is worthy of clinical application.
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