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目的：观察参附注射液对减少阿霉素所致心脏毒性的作用。方法：将住院患者205人随机分为常规化疗组（n1=98），常规用含阿霉素的化疗方案；加用参附注射液组（n2=107），于应用阿霉素前用参附注射液，两组病人均于用药后2小时作常规心电图检查。结果：常规用阿霉素化疗组心电图异常发生率为36．7％，加用参附注射液组为13．1％，两组比较，差异有极显著意义（P＜0．01）。结论；参附注射液可明显减少阿霉素引起的心脏毒性反应。
Objective: To observe the effect of Shenfu injection on reducing cardiotoxicity induced by adriamycin. Methods: 205 inpatients were randomly divided into conventional chemotherapy group (n1=98), routine chemotherapy with doxorubicin, and Shenfu injection group (n2=107). Before use of doxorubicin, With injection, both groups of patients were routinely performed electrocardiogram 2 hours after administration. RESULTS: The incidence of abnormal electrocardiogram was 36.7% in the conventional adriamycin chemotherapy group and 13.1% in the Shenfu Injection group. There was a significant difference between the two groups (P<0.01). Conclusion: Shenfu injection can significantly reduce the cardiotoxicity induced by doxorubicin.