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为探讨原发性开角型青光眼的发病机理,进行了29例原发性开角型青光眼病人的血浆TXA_2-PGI_2的测定,并选择20例健康人作为对照。测定结果:青光眼组的血浆TXA_2均比正常对照组有较显著升高(P<0.01)。说明血浆中的TXA_2-PGI_2动态平衡失调参与了原发性开角型青光眼的发病机理。
To investigate the pathogenesis of primary open-angle glaucoma, 29 cases of primary open-angle glaucoma were measured in plasma TXA 2 -PGI 2, and 20 healthy controls were selected. The results showed that plasma TXA 2 in glaucoma group was significantly higher than that in normal control group (P <0.01). TXA 2-PGI 2 plasma homeostasis is involved in the pathogenesis of primary open-angle glaucoma.