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本文对25例重症慢性阻塞性肺疾病伴营养不良的住院患者进行了营养评价。12例患者进行了短期的静脉营养支持治疗,13例对照者仅给予抗感染,平喘,止咳等处理,以观察短期营养支持的效果及血清氨基酸水平的变化。结果提示:静脉营养支持可明显提高血清中某些氨基酸、血清蛋白水平(p<0.05或p<0.01),改善营养状况,但治疗后尿氮、尿肌酐及尿3─甲基组氨酸(3-MH)的排出并不比对照组明显下降。表明对此类患者进行静脉营养支持虽可促进机体蛋白质的合成,但并不能明显降低蛋白质分解率。
In this paper, 25 patients with severe chronic obstructive pulmonary disease with malnutrition in hospital nutrition evaluation. Twelve patients received short-term intravenous nutrition support. Thirteen controls were given only anti-infective, antiasthmatic and cough-relieving treatments to observe the effects of short-term nutritional support and serum amino acid levels. The results suggest that: intravenous nutritional support can significantly increase serum levels of some amino acids, serum protein (p <0.05 or p <0.01), improve nutritional status, but after treatment of urinary nitrogen, urinary creatinine and urine 3 ─ methyl Histidine (3-MH) was not significantly lower than the control group. This suggests that intravenous nutritional support for such patients may promote the synthesis of protein in the body, but does not significantly reduce the rate of protein degradation.