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目的:观察莪黄汤联合化疗对直肠癌保肛术患者前切除术后排便功能及生活质量的影响。方法:将40例直肠癌术后患者随机分为治疗组22例和对照组18例,2组均采用FOLFOX4方案化疗,治疗组加用莪黄汤保留灌肠治疗,疗程为4周。治疗4周后,观察2组排便功能以及生活质量变化情况。结果:排便次数、大便失禁频次评分、大便能否在15分钟内排完、是否存在不能完全排净的感觉治疗组治疗前后比较差异有统计学意义(P<0.01或P<0.05),2组治疗后组间比较差异有统计学意义(P<0.01);排便次数、大便失禁频次评分对照组治疗前后比较差异有统计学意义(P<0.01或P<0.05),而大便能否在15分钟内排完、不能完全排净的感觉对照组治疗前后比较差异无统计学意义(P>0.05)。治疗组生活质量改善例数明显高于对照组(P<0.05)。结论:莪黄汤可有效改善前切除术后患者排便功能,能提高患者生活质量,值得临床推广及进一步研究。
Objective: To observe the effects of Curcuma Yellow Curcuma combined with chemotherapy on defecation and quality of life after anterior resection in rectal cancer patients undergoing anal sphincter preservation. Methods: Forty patients with postoperative rectal cancer were randomly divided into treatment group (n = 22) and control group (n = 18). The two groups were treated with FOLFOX4 regimen. The treatment group was treated with retention enema of Curcuma yellow soup for four weeks. After 4 weeks of treatment, two groups of defecation function and quality of life changes were observed. Results: The number of defecation, frequency of fecal incontinence, the stool can be discharged within 15 minutes, whether there is a feeling of incomplete discharge of the treatment group before and after treatment was statistically significant difference (P <0.01 or P <0.05), 2 There was significant difference between the two groups after treatment (P <0.01). The number of defecation and fecal incontinence frequency score in the control group before and after treatment were significantly different (P <0.01 or P <0.05) End row within the row, can not completely drain the feeling of the control group before and after treatment was no significant difference (P> 0.05). The quality of life in the treatment group was significantly higher than the control group (P <0.05). Conclusion: Curcuma yellow soup can effectively improve the defecation function of patients after pre-resection, can improve the quality of life of patients, worthy of clinical promotion and further study.