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报告了16例Barrett食管癌的形态学特点并探讨了其组织发生来源。16例Barrett食管癌皆为腺癌,瘤体全部或大部位于食管内,9例见柱状上皮(Barrett上皮)并排除了肿瘤来自胃腺或食道粘液腺的可能,诊断是可靠的。16例中肿瘤体积最小者1cm,最大者10.5cm,7例呈膨胀性生长,9例呈浸润性生长,11例浸润食管壁全层,14例有淋巴结转移,关于组织发生来源,在有Barrett上皮的9例中8例有肠上皮化生,7例有非典型增生,6例有腺瘤,而15例对照组中除6例有轻度肠化生外,无腺瘤及非典型增生。作者认为Barrett食管癌来源于Barrett上皮。
The morphological characteristics of 16 cases of Barrett’s esophageal cancer were reported and the origin of histogenesis was discussed. All 16 cases of Barrett’s esophageal cancer were adenocarcinomas. All or most of the tumors were located in the esophagus. In 9 cases, columnar epithelium (Barrett’s epithelium) was seen and the possibility of tumors coming from the stomach glands or esophageal mucin glands was diagnosed. The diagnosis was reliable. Among the 16 cases, the smallest tumor size was 1cm, the largest was 10.5cm, 7 cases showed expansive growth, 9 cases showed invasive growth, 11 cases infiltrated the esophageal wall and 14 cases had lymph node metastasis. Among the 9 cases of Barrett’s epithelium, 8 cases had intestinal metaplasia, 7 cases had atypical hyperplasia, 6 cases had adenoma, and 15 cases in the control group had mild intestinal metaplasia, no adenoma and atypicality except 6 cases. Hyperplasia. The authors believe that Barrett’s esophageal cancer originates from Barrett’s epithelium.