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目的:通过本研究来讨论甲氨喋呤联合米非司酮对于宫外孕患者的保守治疗的临床效果。方法:分析2013年的76例宫外孕患者的临床症状,将这76例患者随机分为实验组和对照组两组,每组38例,对照组给予米非司酮治疗,实验组除了给予米非司酮治疗外,同时给予甲氨喋呤治疗。在这期间,观察并分析两组患者的临床症状、盆腔包块的消退时间、血β-HCG值达到正常的时间。结果:实验组的治愈率(89.47%)比对照组的治愈率(68.42%)有明显的提高,且两者的差异有统计学意义(P<0.05)。对两组患者的临床症状、血β-HCG值、住院期间的身理反应以及包块的消退进行分析比较,实验组在差异上比对照组的情况较好,两者的差异具有统计学意义(P<0.05)。结论:甲氨喋呤联合米非司酮保守治疗宫外孕的方法取得了较好的临床效果,且其在临床的不良反应也较少,值得在临床上广泛应用。
OBJECTIVE: To discuss the clinical efficacy of methotrexate in combination with mifepristone for conservative treatment of ectopic pregnancy in this study. Methods: The clinical symptoms of 76 ectopic pregnancy patients in 2013 were analyzed. The 76 patients were randomly divided into experimental group and control group, with 38 cases in each group. The control group was treated with mifepristone, Methyl ketone treatment, while given methotrexate treatment. During this period, the clinical symptoms of the two groups were observed and analyzed. The pelvic mass subsidence time and the blood β-HCG value reached the normal time. Results: The cure rate of the experimental group (89.47%) was significantly higher than that of the control group (68.42%), and the difference was statistically significant (P <0.05). The clinical symptoms, blood β-HCG value, physical response during hospitalization and the regression of mass in two groups were compared and analyzed, the experimental group was better than the control group in the difference, the difference between the two groups was statistically significant (P <0.05). Conclusion: Methotrexate combined with mifepristone conservative treatment of ectopic pregnancy has achieved good clinical results, and its clinical adverse reactions are less, it is widely used in clinical practice.