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目的观察青英颗粒对副流感病毒Ⅰ型的体外作用,方法采用体外抑制病毒致细胞病变作用(CPE)的方法:用制备好的青英颗粒含药血清及对照组(感冒退热冲剂、病毒唑颗粒剂)含药血清抑制感染病毒的Hep-2细胞,用MTT法观测青英颗粒含药血清对病毒致细胞病变的抑制作用。结果青英颗粒高、中剂量含药血清对副流感病毒Ⅰ型的抑制作用与药物对照组、模型组比较差异显著。结论青英颗粒的抗病毒作用优于感冒退热冲剂、病毒唑,是治疗急性上呼吸道感染的良好抗病毒中成药。
Objective To observe the effect of Qingying Granules on parainfluenza virus type I in vitro. Methods The method of inhibiting viral cytopathogenic effect (CPE) in vitro was used: prepared Qingyin granule drug-containing serum and control group (cold antipyretic granules, virus The drug-containing serum of the azole granules inhibited the Hep-2 cells infected with the virus, and the inhibitory effect of the Qingying Granule containing drug serum on the virus-induced cytopathic effect was observed by MTT assay. Results The inhibitory effect of Qingying Granules’ high- and medium-dose drug-containing serum on parainfluenza virus type I was significantly different from the drug control group and the model group. Conclusion The antiviral effect of Qingying Granules is better than that of flu and antiviral granules. It is a good antiviral proprietary Chinese medicine for the treatment of acute upper respiratory tract infections.