论文部分内容阅读
[目的]探讨子宫内膜癌手术后辅助放射治疗的疗效及其预后因素。[方法]接受术后辅助放疗的子宫内膜癌患者106例,直线加速器盆腔野体外照射,24例加阴道施源器HDR腔内后装治疗。按患者年龄、手术病理分期、肌层浸润、病理类型、病理分级、淋巴结转移6个观察指标分析与5年生存率的关系。[结果]全组5年生存率53.6%。年龄、手术病理分期、肌层浸润、病理类型、淋巴结转移与术后生存率显著相关(P<0.05),病理分级与生存率无明显相关(P>0.05)。[结论]子宫内膜癌手术后辅助放射治疗的疗效肯定,年龄、手术病理分期、肌层浸润、病理类型、淋巴结转移是影响子宫内膜癌生存率的预后因素。
[Objective] To investigate the efficacy and prognostic factors of adjuvant radiotherapy after endometrial cancer surgery. [Method] 106 patients with endometrial cancer receiving postoperative adjuvant radiotherapy, external beam irradiation of linear accelerator in the pelvic region, and 24 patients with vaginal applicator HDR intracavitary afterloading treatment. According to the age of the patients, the pathological stage of the operation, the myometrial invasion, pathological type, pathological grade and lymph node metastasis, the relationship between the 5-year survival rate and the 6 observation indexes was analyzed. [Results] The 5-year overall survival rate was 53.6%. Age, pathological stage, myometrial invasion, pathological type, lymph node metastasis and postoperative survival rate were significantly correlated (P <0.05). There was no significant correlation between pathological grade and survival rate (P> 0.05). [Conclusion] The efficacy of adjuvant radiotherapy after endometrial cancer operation is confirmed. Age, surgical pathological stage, myometrial invasion, pathological type and lymph node metastasis are the prognostic factors of the survival rate of endometrial cancer.