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患者女,67岁.因淋巴瘤入院治疗,在疾病完全缓解期(CR期)受寒后出现咽痛伴低热,在青霉素皮试阴性的情况下给予生理盐水100ml加氨灭菌1.2g静注.30分钟后,全身皮肤搔痒并心慌、寒战、颜面及躯干皮肤发红,BP 11/7kPa,立即吸氧、肌注苯海拉明等,症状消失,约4～5小时后,全身皮肤颜色转为正常,出现散在皮肤水泡,1cm×2cm～6cm×7cm不等,被挤压后破溃有组织液渗出,触痛(+),经支持、
Female patient, age 67. Due to hospitalization for lymphoma, sore throat and fever occurred after chilling in the complete remission of disease (CR stage), saline 100 ml plus ammonia sterilization 1.2 g intravenously in the case of penicillin skin test negative .30 minutes later, systemic skin itching and palpitation, chills, facial and trunk skin redness, BP 11 / 7kPa, immediately oxygen, intramuscular injection of diphenhydramine, the symptoms disappear, about 4 to 5 hours after the whole body skin color Turned to normal, there are scattered skin blisters, ranging from 1cm × 2cm ~ 6cm × 7cm, crushed after squeezing organized fluid seepage, tenderness (+), after the support,