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目的:探讨新生儿胆红素脑病的病因以及观察治疗效果。方法:总结56例新生儿胆红素脑病的临床资料,对病因以及治疗效果进行总结和分析。结果:新生儿胆红素脑病的病因主要为:溶血病(53.6%)和感染性疾病(32.1%);观察组28例患儿除进行蓝光照射、丙种球蛋白、白蛋白、抗感染等常规治疗外给予换血治疗;与对照组给予常规治疗的28例患儿进行比较,治疗后的NBNA评分改善情况,差异具统计学意义(P<0.05)。结论:溶血和感染性疾病是导致新生儿胆红素脑病主要病因,换血等综合治疗可有效改善患儿的NBNA评分,是临床有效的治疗方法。
Objective: To explore the etiology of neonatal bilirubin encephalopathy and to observe the therapeutic effect. Methods: The clinical data of 56 cases of neonatal bilirubin encephalopathy were summarized, the etiology and therapeutic effect were summarized and analyzed. Results: The main causes of neonatal bilirubin encephalopathy were hemolytic disease (53.6%) and infectious diseases (32.1%). In the observation group, 28 cases of children with bilirubin encephalopathy except blue light, gamma globulin, albumin, The treatment of transfusions was given outside the treatment group. The improvement of NBNA score after treatment was compared with that of the control group (n = 28). The difference was statistically significant (P <0.05). Conclusion: Hemolytic and infectious diseases are the main causes of neonatal bilirubin encephalopathy. Transfusion and other comprehensive treatment can effectively improve the NBNA score in children. It is a clinically effective treatment.