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目的观察丙泊酚联合芬太尼静脉麻醉用于人工流产术临床镇痛效果及安全性。方法选择健康早期要求终止妊娠、无人工流产禁忌证的妇女120例,随机分为观察组60例,术前静脉缓慢注射芬太尼50μg+丙泊酚(每公斤体重2.0mg);对照组60例,术前未给任何药物,手术方法两组相同。结果镇痛效果、宫颈松弛程度、人工流产综合征发生和术中不良反应,两组差异具有统计学意义(P<0.01),两组术中出血量比较差异无统计学意义(P>0.05)。结论芬太尼丙泊酚用于人流效果良好,镇痛作用强,宫口松驰发生率高,不增加阴道出血量。使用芬太尼丙泊酚方法简便、安全、镇痛效果明显,但芬太尼和丙泊酚都具有短暂的呼吸抑制现象,使用这两种药物实施无痛人流时,应准备基本的抢救设备和氧气,维持呼吸道通畅。
Objective To observe the clinical analgesic effect and safety of propofol combined with fentanyl intravenous anesthesia for artificial abortion. Methods A total of 120 women with early pregnancy termination and no contraindications of induced abortion were selected and randomly divided into observation group (60 cases) and fentanyl (50μg + propofol 2.0 mg). The control group (60 cases) , Did not give any preoperative drugs, surgical methods of the same two groups. Results The analgesic effect, the degree of cervical relaxation, the incidence of induced abortion syndrome and the intraoperative adverse reactions had statistical significance (P <0.01). There was no significant difference in the amount of blood loss between the two groups (P> 0.05) . Conclusions Fentanyl propofol has good effect on abortion, strong analgesic effect and high incidence of cervix relaxation without increasing the amount of vaginal bleeding. The use of fentanyl propofol method is simple, safe, analgesic effect is obvious, but both fentanyl and propofol have a short respiratory depression, the use of these two drugs when painless, you should prepare the basic rescue equipment And oxygen, to maintain airway patency.