在临床上抗生素的广泛应用,促使对抗生素敏感的细菌逐渐减少和耐药的细菌日益增多;同时,对多种抗生素耐药的菌株也有增多趋势,这与耐药性在细菌基因中蓄积并在其群体中扩展有关.由于葡萄球菌属、大肠杆菌、绿脓杆菌、克雷伯菌属、变形杆菌 The widespread use of antibiotics in clinical practice has led to an ever-increasing number of bacteria that are sensitive to antibiotics and an increasing number of bacteria resistant to antibiotics. In the meantime, there is also an increasing trend of resistance to multiple antibiotics, which accumulates with bacterial resistance in Its expansion in the group related to Staphylococcus, Escherichia coli, Pseudomonas aeruginosa, Klebsiella, Proteus