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目的研究分析呼吸机相关性下呼吸道感染病原菌检测及耐药情况。方法选择2015年6月~2015年6我院收治的呼吸机相关性下呼吸道感染患者202例,收集其痰液标本,并分离获得病原菌进行检测及药敏试验。结果本组202例患者的痰液标本共检测出310株致病菌,其中革兰阴性菌268株(86.45%);前3位依次为鲍曼不动杆菌、洋葱伯克霍尔德菌、铜绿假单胞菌;这3种细菌的药敏试验结果显示,均为多重耐药菌,并且耐药率较高。结论呼吸机治疗容易引发下呼吸道感染,临床应常规痰培养进行病原菌检测,合理选择抗菌药物,避免病原菌耐药性的产生。
Objective To study the detection and drug resistance of respiratory pathogens in ventilator-associated lower respiratory tract infection. Methods From June 2015 to 2015, 202 patients with ventilator-associated lower respiratory tract infection admitted to our hospital from June 2015 to June 2015 were collected and their sputum samples were collected. Pathogenic bacteria were isolated and tested for drug susceptibility. Results A total of 310 pathogenic bacteria were detected in sputum from 202 patients in this study, of which 268 were gram-negative bacteria (86.45%). The top three followed by Acinetobacter baumannii, Burkholderia cepacia, Pseudomonas aeruginosa; The results of drug susceptibility test of the three kinds of bacteria showed that they were all multi-drug-resistant bacteria with high resistance rate. Conclusions Ventilator treatment is likely to cause lower respiratory tract infection. Pathogens should be detected routinely in sputum culture, and antibacterial drugs should be selected reasonably to avoid the emergence of drug resistance of pathogens.