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目的观察不同方法治疗妊娠期合并尖锐湿疣(condyloma acuminatum,CA)的疗效。方法对2005年6月至2010年5月就诊于天津市中心妇产科医院的妊娠合并CA的200例患者相关资料进行回顾性比较研究,其中A组69例采用VWYⅢ型微波治疗仪治疗,B组67例采用CO2激光治疗,C组64例采用50%三氯醋酸上药治疗。结果治疗后随访3个月,A组治愈60例(86.96%),复发15例(21.74%);B组治愈61例(91.04%),复发16例(23.88%);C组治愈54例(84.38%),复发4例(6.25%)。3种方法治愈率比较无统计学意义(P>0.05);复发率C组较A、B两组低(χ2=8.36,P<0.05)。结论微波、CO2激光和50%三氯醋酸局部药物治疗妊娠期CA均安全可靠,治愈率高,50%三氯醋酸复发率较低,优于另外两种方法。
Objective To observe the curative effect of different methods on congenital condyloma acuminatum (CA) during pregnancy. Methods A retrospective comparative study was conducted on 200 cases of pregnant women with CA who were treated in Tianjin Obstetrics and Gynecology Hospital between June 2005 and May 2010. A group of 69 patients were treated with VWY Ⅲ microwave treatment instrument and B Group 67 cases treated with CO2 laser, C group 64 cases treated with 50% trichloroacetic acid. Results A total of 60 cases (86.96%) were cured and 15 cases (21.74%) were cured in group A. 61 cases (91.04%) were cured and 16 cases (23.88%) were cured in group B. 54 cases were cured 84.38%), recurrence in 4 cases (6.25%). The cure rates of the three methods were not statistically significant (P> 0.05). The recurrence rate in group C was lower than that in group A and B (χ2 = 8.36, P <0.05). Conclusion Microwave, CO2 laser and 50% trichloroacetic acid local medicine are safe and reliable during pregnancy. The cure rate is high and the relapse rate of 50% trichloroacetic acid is lower than the other two methods.