多囊卵巢综合征(PCOS)是高雄激素性不排卵性不孕的最常见的原因,是一种发病多因性,临床表现为多态性的综合征。近年发现胰岛素抵抗(IR)是PCOS的发病环节之一,也为其临床治疗提供了理论依据,开辟治疗的新途径。综述PCOS患者的IR机制,IR在PCOS发病中的病理生理变化及对患者的影响及相关治疗进展。 Polycystic ovary syndrome (PCOS) is the most common cause of steroid-induced infertility in Kaohsiung and is a syndrome characterized by multiple causes and clinical manifestations. In recent years, insulin resistance (IR) is one of the pathogenesis of PCOS, but also provides a theoretical basis for its clinical treatment, open up new avenues of treatment. The mechanism of IR in PCOS patients, the pathophysiological changes of IR in the pathogenesis of PCOS, the influence on the patients and the related treatment progress were reviewed.