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目的 观察前部缺血性视神经病变 (anterior ischemic optic neuropathy,AION)的吲哚青绿和荧光素眼底血管造影 (indocyanine green angiography and fundus fluorescein angiography,ICGA& FFA)特征 ,探讨 AION的病因和发病机制 ,以及 ICGA和 FFA在 AION诊断和研究方面的价值。 方法 对比分析 AION患者 31例 32只眼和非 AION眼底病患者 38例 38只眼 ICGA& FFA同步检查的图像以及AION患者的视野检查资料。 结果 AION组中视盘全部或部分位于脉络膜血液供应分水带内的眼数显著多于非 AION(P<0 .0 0 5 ) ;所有接受检查眼通过视盘的分水带都为垂直状 ,视盘两侧脉络膜血管充盈较上下方为快。AION患者的分水带分型与视盘缺血部位存在明确的对应关系。ICGA早期视盘无荧光 ,晚期视盘缺血区均无荧光 ,非缺血区主要表现为不均匀荧光。 结论 AION的发病与盘周脉络膜血液供应状态有关。 ICGA在对 AION的诊断和研究方面比 FFA具有更大的价值。
Objective To observe the characteristics of indocyanine green fundi fundus and fundus fluorescein angiography (ICGA & FFA) in anterior ischemic optic neuropathy (AION) and explore the etiology and pathogenesis of AION. The value of ICGA and FFA in AION diagnosis and research. Methods Thirty-two cases of 32 patients with AION and 38 patients with non-AION fundus were retrospectively analyzed by ICGA & FFA simultaneous examination and visual field examination of AION patients. Results In the AION group, the number of eyes with all or part of the optic disc in the choroidal blood supply was significantly more than that of the non-AION group (all P <0.05); in all the eyes under examination, the watershed of the optic disc was vertical, Both sides of the choroidal blood vessels filled faster than the upper and lower. There is a clear correspondence between watershed typing of AION patients and ischemic sites of optic disc. ICGA early disc no fluorescence, late optic disc ischemic area were no fluorescence, non-ischemic area is mainly manifested as uneven fluorescence. Conclusion The incidence of AION is related to the status of choroidal blood supply. ICGA is more valuable than FFA in the diagnosis and research of AION.