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用ELISA 法对110 名健康孕产妇进行血清抗- HGV 测定, 阳性和可疑阳性者再用RT-PCR 检测血清HGV RNA,并对HGV RNA 阳性孕产妇的新生儿脐血和婴儿血进行HGV RNA 检测。结果110 名孕产妇中有7 人(6 .36% ) 抗- HGV 阳性,8 人可疑阳性。其中4 人被检测到HGV RNA,阳性率26 .66 % (4/15) 。她们所产的4 名婴儿中2 人血清HGV RNA 阳性,提示HGV 的母婴传播率为50% (2/4) ,剖宫产可能具有减轻HGV 母婴传播的作用。
HGV RNA was detected by reverse transcription-polymerase chain reaction (RT-PCR) in 110 healthy pregnant women with positive and suspicious positives by ELISA, and HGV RNA was detected in neonates with HGV RNA positive pregnant women . Results Of the 110 pregnant women, 7 (6.36%) were positive for anti-HGV and 8 were positive for suspicion. Four of them were detected HGV RNA, the positive rate of 26. 66% (4/15). Serum HGV RNA was positive in 2 out of 4 babies they produced, suggesting a 50% (2/4) maternal-to-infant transmission rate of HGV. Caesarean section may have the effect of reducing mother-infant HGV transmission.