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1895年Oliver和Sch(?)fer证明肾上腺髓质中存在血压上升物质(肾上腺素)以来,有关儿茶酚胺的合成、代谢及与各脏器关系获得许多知识,并提出了新的研究方向。儿茶酚胺是属于生理活动性胺类之一,在机体内广泛存在,虽然微量但具有强的生理活性。为此研究儿茶酚胺机体内作用上,需要特异的、高敏感度检出法。近年来各种检查法的进步,可以测出pg程度的儿茶酚胺。此次作者以维修容易、操作简单、特异性敏感、高速度液体色谱分析(HPL C)。电化学验测器进行了儿茶酚胺研究,以探讨妊娠期儿茶酚胺的动态,特别是研究了关于与妊娠高血压综合征的关系。过去已有多人报告妊娠期去甲肾上腺素(NE)、肾上腺素(E)有变动,测定方法以放射酶法为主,
Since Oliver and Schöfer in 1895 demonstrated the presence of blood pressure-boosting substances (adrenaline) in the adrenal medulla, much is known about the synthesis and metabolism of catecholamines and the relationship with the various organs, and new research directions are proposed. Catecholamines belong to one of the physiologically active amines, which are widely present in the body, although they are trace but have strong physiological activity. To study the role of catecholamines in the body, the need for specific, high sensitivity detection method. In recent years the progress of various examination methods, can determine the degree of pg catecholamines. The author is easy to maintain, easy to operate, specific and sensitive, high-speed liquid chromatography (HPL C). Electrochemical detector catecholamine study to explore the dynamic catecholamine during pregnancy, in particular, on the relationship with pregnancy-induced hypertension syndrome. In the past there have been many reports of norepinephrine (NE) during pregnancy, epinephrine (E) have changed the determination of the method to the main enzyme method,