Using SnxTi1-xO2 as carriers, CuO/Sn0.9Ti0.1O2 and CuO/Sn0.7Ti0.3O2 catalysts with different loading amounts of copper oxide (CuO) were prepared by an impregnation method. The catalytic properties of CuO/Sn0.9Ti0.1O2 and CuO/Sn0.7Ti0.3O2 were examined using a microreactor-gas chromatography (GC) NO+CO reaction system and the methods of BET (Brunauer-Emmett-Teller), TG-DTA (themogravimetric and differential thermal analysis), X-ray diffraction (XRD) and H2-temperature programmed reduction (TPR). The results showed that NO conversions of Sn0.9Ti0.1O2 and Sn0.7Ti0.3O2 were 47.2% and 43.6%respectively, which increased to 95.3% and 90.9% at 6 wt% CuO loading. However, further increase in CuO loading caused a decrease in the catalytic activity. The nitrogen adsorption-desorption isotherm and pore-size distribution curve of Sn0.9Ti0.1O2 and Sn0.7Ti0.3O2 represented type Ⅳ of the BDDT (Brunauer, Deming, Deming and Teller) system and a typical mesoporous sample.There were two CuO diffraction peaks (2θ 35.5° and 38.7°), and the diffraction peak areas increased with increasing CuO loading.TPR analysis also detected three peaks (α, β and γ) from the CuO-loaded catalysts, suggesting that the α peak was the reduction of the highly dispersed copper oxide, the β peak was the reduction of the isolated copper oxide, and the γ peak was the reduction of crystal phase copper oxide. In addition, a fourth peak (δ) of the catalysts meant that the SnxTi1-xO2 mixed oxides could be reductive.