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目的:评价爱普列特(Epristeride)联合高特灵(Hytrin)治疗良性前列腺增生(BPH)的安全性、有效性。方法:48例诊断为BPH的患者,年龄50~80岁,平均(65±9.20)岁。给予高特灵5 mg,1次/每晚,共3月;爱普列特片5mg,2次/天口服,共6月。观察治疗前后国际前列腺症状评分(IPSS)、最大尿流率(Qmax)、前列腺体积(V)及膀胱残余尿量(Ru)的变化。结果:45例完成观察,服药3月后,除前列腺体积外,其他指标均有明显改善;6月后,各项指标均明显改善。治疗过程中未发现明显不良反应。结论:爱普列特片与高特灵联用治疗BPH安全、有效。
Objective: To evaluate the safety and efficacy of Epristeride combined with Hytrin in the treatment of benign prostatic hyperplasia (BPH). Methods: Forty-eight patients diagnosed with BPH were aged 50 to 80 years (mean, 65 ± 9.20 years). Gortolol given 5 mg, 1 time / night, a total of 3 months; Epstein tablets 5mg, 2 times / day orally, a total of 6 months. The changes of International Prostate Symptom Score (IPSS), Qmax, Prostate volume (V) and residual urine volume (Ru) before and after treatment were observed. Results: 45 cases completed the observation. After taking medicine for 3 months, except for the volume of the prostate, other indexes improved obviously. After 6 months, all the indexes were significantly improved. No obvious adverse reactions were found during the treatment. Conclusion: Combination of Epsilon tablet and Gortolux is safe and effective in the treatment of BPH.