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目的通过对2007～2008年血液科住院患者医院感染分析,了解病原菌分布情况,指导临床经验性用药。方法对医院血液科2007年1月～2008年8月住院患者中临床分离出病原菌的分布情况进行分析。结果在各种培养物阳性100例菌株中,革兰阴性菌占52%,革兰阳性菌占35%,真菌占13%,血培养阳性率为36%,痰培养阳性率为27%,尿培养阳性率为21%,分泌物,咽拭子及便培养阳性率分别为7%、6%、3%,引起感染病原菌中排列前3位的分别为大肠埃希菌、表皮葡萄球菌、肺炎克雷伯菌。结论2007～2008年医院血液科住院患者医院感染的致病菌以革兰阴性杆菌为主,临床上在细菌培养结果出来前建议用以革兰阴性菌为主,兼顾革兰阳性菌的广谱抗菌活性强的抗菌药物。
Objective To analyze the distribution of pathogenic bacteria in nosocomial hematology inpatients from 2007 to 2008 and to guide clinical experience. Methods The clinical isolates of pathogenic bacteria in hospitalized patients from January 2007 to August 2008 were analyzed. RESULTS: Gram-negative bacteria accounted for 52%, Gram-positive bacteria accounted for 35%, fungi accounted for 13%, blood culture positive rate was 36%, sputum culture positive rate was 27%, urine of 100 The positive rate of culture was 21%, the positive rate of secretions, throat swabs and culture was 7%, 6% and 3% respectively. The top three pathogens were Escherichia coli, Staphylococcus epidermidis, pneumonia Klebsiella. Conclusions Hospital-acquired inpatient hematology patients from 2007 to 2008 are mainly Gram-negative bacilli. In clinic, it is recommended that Gram-negative bacteria should be used before the results of bacterial culture, taking into account the broad spectrum of Gram-positive bacteria Antibacterial activity of antibacterial drugs.