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目的:探讨维持性血液透析尿毒症患者失眠改善方法。方法:对维持性血液透析尿毒症失眠者158例采用血液透析滤过,应用匹兹堡睡眠质量指数(Pittsburgh sleep quality index,PSQI)量表作为评定睡眠量化指标,并进行治疗前、后自身对照,观察患者失眠改善情况。结果:治疗2个月后,25例患者消除失眠,52例有效,59例好转,22例无自觉改善;患者主观睡眠质量、入睡时间、睡眠时间、催眠药物、日间功能障碍、PSQI总分差异有统计学意义(P<0.01),治疗前、后睡眠障碍差异有统计学意义(P<0.05)。结论:血液透析滤过可改善维持性血液透析尿毒症患者失眠状况。
Objective: To investigate the method of insomnia improvement in patients with maintenance hemodialysis uremia. Methods: 158 cases of maintenance hemodialysis uremic insomnia were hemodiafiltration, Pittsburgh sleep quality index (PSQI) scale as a measure of sleep quantification, and before and after treatment, self-control, observation Patients with insomnia to improve the situation. Results: After 2 months of treatment, insomnia was eliminated in 25 patients, effective in 52 patients, improvement in 59 patients, and no improvement in 22 patients. The subjective sleep quality, sleep time, sleep time, hypnotic drugs, daytime dysfunction, PSQI score The difference was statistically significant (P <0.01), before and after treatment, there was a significant difference in sleep disorders (P <0.05). Conclusion: Hemodiafiltration can improve insomnia in maintenance hemodialysis patients.