现代抗惊厥疗法的历史可以追溯到二十世纪初。1912年即介绍了苯巴比妥,1938年又介绍了苯妥英钠,至今这些药物都是治疗癫癎的首选药物。近十多年来,发现苯并二氮杂(?)衍生物有镇静和抗惊厥性质。人们对来自这一衍生物的安定和硝基安定,在治疗各种类型的癫癎方面进行了研究。与其它抗惊厥药比较,尽管安定有相对地安全而毒性小的优点,但却很少长期单独使用。在临床实践 Modern anti-convulsive therapy dates back to the early twentieth century. Phenobarbital was introduced in 1912, phenytoin sodium was introduced in 1938, and so far these drugs are the drug of choice for the treatment of epilepsy. For more than a decade, benzodiazepine (?) Derivatives have been found to have sedative and anticonvulsant properties. Stability and nitrazepam from this derivative have been studied in the treatment of various types of epilepsy. Compared with other anticonvulsants, sedatives have the advantage of being relatively safe and less toxic, but seldom long-term use alone. In clinical practice