盐酸丁卡因为长效局麻药，作用比盐酸普鲁卡因强１０倍［１］。盐酸丁卡因注射易致疼痛，组织变形以及潜在的系统吸收等不良反应，应用离子导入则可避免这些不良反应。为此采用均匀设计法，对盐酸丁卡因离子导入凝胶进行处方筛选。１　材料和仪器盐酸丁卡因（第二军医大学朝晖 Because of long-acting local anesthetics, tetracaine hydrochloride is 10 times more potent than procaine hydrochloride [1]. Tetracaine hydrochloride injection is prone to cause pain, tissue deformation and potential systemic absorption and other adverse reactions, the application of iontophoresis can avoid these adverse reactions. For this purpose, a uniform design method was used to prescribe tetracaine hydrochloride ion-exchange gel. 1 Materials and instruments Tetracaine hydrochloride (Second Military Medical University Zhaohui