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[目的]探讨手足口病流行特征,为手足口病防治工作提供科学依据。[方法]分析2008年濮阳市医疗机构报告的手足口病临床诊断病例临床资料和流行病个案调查资料。[结果]2008年濮阳市报告手足口病581例,发病率为15.89/10万,为散发疫情,未出现暴发疫情。发病率(/10万),男性为20.74,女性为10.51(P<0.01);0岁为56.81,1~3岁为319.14,4~9岁为29.81,10~13岁为7.36(P<0.01);农村为14.85,城区为18.32(P<0.05)。5~7月发病数占全部病例的83.48%。检测35例病人发病1周内标本68份,肠病毒EV71核酸阳性率为80.06%;病人血清32份,肠病毒EV71核酸全部阴性。[结论]2008年濮阳市手足口病以肠病毒EV71感染为主,男性、1~3岁儿童、城区居民发病率较高。
[Objective] To explore the epidemic characteristics of HFMD and provide a scientific basis for the prevention and treatment of HFMD. [Methods] To analyze the clinical data and epidemiological survey data of hand-foot-mouth disease reported by medical institutions in 2008 in Puyang. [Results] In 2008, 581 cases of hand-foot-mouth disease were reported in Puyang City, the incidence rate was 15.89 / 100 000, which was an outbreak of epidemic situation without outbreak of outbreak. (P <0.01); age at age 0 was 56.81; age at age 3 was 319.14; age at age 9-9 was 29.81; at age 7.3 to 13 years was 7.36 (P <0.01) ), 14.85 in rural areas and 18.32 in urban areas (P <0.05). The number of cases from May to July accounted for 83.48% of all cases. Sixty-eight samples of 35 patients were detected within 1 week after infection. The positive rate of EV71 was 80.06%. The serum of patients was 32 and all the EV71 nucleic acids of enterovirus were negative. [Conclusion] In 2008, the EV71 infection in hand-foot-mouth disease in Puyang city was the main cause. The prevalence of male, 1 to 3 years old children and urban residents was high.