Two symmetrical unsaturated acids isolated from Viscum album

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In the present study,two new acetylene conjugate compounds,dibutyl (2Z,6Z)-octa-2,6-dien-4-yne dioate (1),and dibutyl (2E,6E)-octa-2,6-dien-4-yne dioate (2),were isolated from the dry stem leaves of Viscum album,along with nine known compounds (3-11).Their structures were confirmed on the basis of spectroscopic data.Compounds 1 and 8 showed antioxidant activity against xanthine oxidase (XOD) and 1,1-diphenyl-2-picrylhydrazyl radical 2,2-diphenyl-1-(2,4,6-trinitrophenyl) hydroxyl (DPPH),with the IC50 of 1.22 and 1.33 μmol.L-1,and the SC50 of 4.34 and 8.22 μmol·L-1,respectively.
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