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目的:探讨应用左卡尼汀对血液透析(HD)患者的血脂及炎性介质的影响。方法:选取我院血液透析中心2008～2011年维持性血液透析患者(1年以上)30例作为研究对象,血液透析后进行1g左卡尼汀每周3次,观察治疗前及1年后患者的血脂及血清CRP水平。结果:观察组患者的血脂及血清CRP水平有明显变化。对比具有统计学意义(P<0.05)。结论:左卡尼汀可以有效改善HD患者微炎症状态及血脂水平。
Objective: To investigate the effect of levocarnitine on blood lipid and inflammatory mediators in hemodialysis (HD) patients. Methods: Thirty cases of maintenance hemodialysis patients (more than one year) from 2008 to 2011 in our hemodialysis center were enrolled in this study. After hemodialysis, 1 g of levocarnitine was administered three times per week. Patients before and after treatment Blood lipids and serum CRP levels. Results: The level of serum lipids and serum CRP in the observation group changed significantly. The comparison was statistically significant (P <0.05). Conclusion: L-carnitine can effectively improve the status of micro-inflammation and lipid levels in HD patients.