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[目的]观察茵芩清肝汤联合硫普罗宁治疗酒精性肝病的临床疗效。[方法]按随机数字表法将110例酒精性肝病患者分为治疗组55例,用茵芩清肝汤联合硫普罗宁0.1 g,3次/d;对照组55例,用硫普罗宁0.1 g,3次/d,连续治疗2个月,观察2组治疗前后血脂、肝功能、肝纤维化指标、肝脏超声等方面的改善情况。[结果]治疗组血脂、肝功能、血清纤维化指标和肝脏超声均有明显改善(P<0.05或P<0.01)。治疗组有效率92.7%(51/55),对照组有效率47.3%(26/55),2组比较差异有统计学意义(P<0.01)。[结论]茵芩清肝汤联合硫普罗宁治疗酒精性肝病疗效理想,值得临床推广应用。
[Objective] To observe the curative effect of Qinqin Qinggan decoction combined with tiopronin on alcoholic liver disease. [Method] According to random number table method, 110 cases of alcoholic liver disease were divided into treatment group (55 cases), Qinqin Qinggan decoction combined with tiopronin 0.1 g, thrice a day, control group (55 cases) g, 3 times / d, continuous treatment for 2 months to observe the two groups before and after treatment of blood lipids, liver function, liver fibrosis, liver ultrasound and other aspects of the improvement. [Results] The blood lipids, liver function, serum fibrosis indexes and liver ultrasonography in treatment group were significantly improved (P <0.05 or P <0.01). The effective rate was 92.7% (51/55) in the treatment group and 47.3% (26/55) in the control group, with significant difference between the two groups (P <0.01). [Conclusion] Qinqin Qinggan Decoction combined with tiopronin in the treatment of alcoholic liver disease is effective and worthy of clinical application.