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目的调查研究不同方案治疗小儿消化性溃疡的临床效果。方法采用随机数字表法将68例消化性溃疡患者分成治疗组和对照组各34例,给予两组奥美拉唑、阿莫西林、克拉霉素药物治疗,治疗组在此基础上增加使用枸橼酸铋钾胶。结果治疗组临床疗效的总有效率为88.2%,与对照组的67.7%比较,差异有统计学意义(P<0.05)。治疗后观察组患者的溃疡消失时间为(37.2±14.2)d,与对照组的(48.4±11.5)d比较,差异有统计学意义(P<0.01)。结论在奥美拉唑、阿莫西林、克拉霉素药物治疗的基础上增加使用枸橼酸铋钾胶,可以有效降低溃疡复发率,提高小儿患者消化性溃疡愈合率,安全性较高。
Objective To investigate the clinical effects of different treatment programs on children with peptic ulcer. Methods Sixty-eight patients with peptic ulcer were divided into treatment group (34 cases) and control group (34 cases) by random number table method. Two groups of omeprazole, amoxicillin and clarithromycin were given. On the basis of this, Bismuth citrate bismuth cement. Results The total effective rate of the treatment group was 88.2%, compared with 67.7% of the control group, the difference was statistically significant (P <0.05). After treatment, the disappearance time of ulcer in the observation group was (37.2 ± 14.2) d, which was significantly different from that of the control group (48.4 ± 11.5) d (P <0.01). Conclusion The addition of bismuth potassium citrate based on omeprazole, amoxicillin and clarithromycin treatment can effectively reduce the recurrence rate of ulcer and improve the healing rate of peptic ulcer in pediatric patients with high safety.