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目的:观察心梗救逆汤联合西药治疗急性心肌梗死的临床效果。方法:将114例患者随机分为研究组与对照组各57例,研究组采取心梗救逆汤联合西药治疗,对照组采用常规西药治疗,2组均治疗3月后观察症状积分改变、心功能指标及炎性因子水平的变化。结果:治疗后,2组超敏C-反应蛋白(hs-CRP)、基质金属蛋白酶-9(MMP-9)、左室舒张末期内径(LVEDD)、左心射血分数(LVEF)与治疗前比较,差异均有统计学意义(P<0.05)。研究组hs-CRP、MMP-9、LVEDD均低于对照组(P<0.05),LVEF高于对照组(P<0.05)。治疗后,2组胸部刺痛、心悸、胸闷、气促症状积分均较治疗前降低(P<0.05),研究组各项症状积分均低于对照组(P<0.05)。结论:心梗救逆汤联合西药治疗急性心肌梗死疗效确切,可显著提高心功能,降低炎性因子表达,改善症状,具有较高的临床应用价值。
Objective: To observe the clinical effect of Xin Yi Jiang Yi Decoction combined with Western medicine in treating acute myocardial infarction. Methods: One hundred and fourteen patients were randomly divided into study group and control group, with 57 cases in each group. The study group was treated with XINYIJIYI decoction combined with western medicine. The control group was treated with conventional western medicine. The symptom scores were changed in both groups after 3 months. Functional indicators and changes in the level of inflammatory cytokines. Results: After treatment, the levels of hs-CRP, MMP-9, LVEDD and LVEF in the two groups were significantly lower than those before treatment Comparison, the differences were statistically significant (P <0.05). The levels of hs-CRP, MMP-9 and LVEDD in the study group were lower than those in the control group (P <0.05), and LVEF was higher in the study group than in the control group (P <0.05). After treatment, the scores of chest pain, heart palpitations, chest tightness and shortness of breath in two groups were all lower than those before treatment (P <0.05). All the symptom scores in the study group were lower than those in the control group (P <0.05). Conclusion: MI combined with western medicine in the treatment of acute myocardial infarction is effective and can significantly improve cardiac function, reduce the expression of inflammatory factors and improve symptoms, and has a high clinical value.