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最近有报道称,甲氰咪呱能使一位Ⅲ型高脂蛋白血症的病人HDL胆固醇浓度增高。进一步的研究表明:10名健康志愿者,每天给甲氰咪呱1克,四周后,发现其HDL胆固醇的浓度增高。我们观察了每天给甲氰咪呱1克或每天给雷尼替丁300mg对HDL和它的次级HDL_2和HDL_3胆固醇浓度的影响。
It has recently been reported that cimetidine can increase HDL cholesterol in a patient with type III hyperlipoproteinemia. Further studies showed that: 10 healthy volunteers were given 1 g of cimetidine daily, and after four weeks, the concentration of HDL cholesterol was increased. We observed the effect of 1 g of cimetidine daily or 300 mg of ranitidine daily on HDL and its secondary HDL_2 and HDL_3 cholesterol concentrations.