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目的评估胸段食道癌术后区域淋巴结转移患者进行三维适形放疗的治疗效果。方法选取2013年7月至2015年6月广东省揭阳市人民医院收治胸段食道癌术后区域淋巴结转移患者98例,随机分为观察组与对照组,各49例,对照组患者接受常规放射治疗,观察组患者接受三维适形放射治疗,放射总剂量60~70 Gy/30~35次,比较两组患者临床疗效、并发症发生情况以及术后1年生存率。结果两组患者临床治疗效果比较,观察组患者治疗总有效率(75.51%)显著高于对照组(53.06%),差异有统计学意义(P<0.05);两组患者并发症发生情况比较[26.53%vs.57.14%],差异有统计学意义(P<0.05);两组患者术后1年生存率比较[79.59%vs.57.14%],差异有统计学意义(P<0.05)。结论应用三维适形放射治疗胸段食道癌术后区域淋巴结转移效果显著,可有效控制病情,并发症少,治疗效果较常规放疗更优。
Objective To evaluate the efficacy of three-dimensional conformal radiotherapy in patients with regional lymph node metastasis after thoracic esophageal cancer surgery. Methods From July 2013 to June 2015, 98 patients with regional lymph node metastasis after thoracic esophagectomy in Jieyang People’s Hospital of Guangdong Province were selected and randomly divided into observation group and control group, with 49 cases in each group. The control group received conventional radiation The patients in the observation group received three-dimensional conformal radiotherapy and the total radiation dose was 60-70 Gy / 30-35 times. The clinical efficacy, complications and 1-year survival rate were compared between the two groups. Results The total effective rate (75.51%) in the observation group was significantly higher than that in the control group (53.06%), the difference was statistically significant (P <0.05). Comparing the two groups of patients with complication [ 26.53% vs.57.14%], the difference was statistically significant (P <0.05). The 1-year survival rate of two groups was 79.59% vs.57.14%, the difference was statistically significant (P <0.05). Conclusions Three-dimensional conformal radiotherapy is effective in treating postoperative regional lymph node metastasis of thoracic esophageal cancer, which can effectively control the disease, with fewer complications and better therapeutic effects than conventional radiotherapy.