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雷公藤甲素是中药雷公藤的主要活性成分。目前雷公藤甲素已被用作多种疾病的治疗,包括:狼疮,肿瘤,类风湿性关节炎,肾病综合征等。雷公藤甲素的主要药理作用包括:抗炎、抗肿瘤、免疫抑制等,近期研究表明雷公藤甲素对心血管疾病及骨质疏松均有保护作用。该文以近期雷公藤甲素的研究进展为基础,对雷公藤甲素的药理作用进行综述。
Triptolide is the main active ingredient of Chinese medicine Tripterygium wilfordii. Triptolide is currently used as a treatment for many diseases including lupus, cancer, rheumatoid arthritis, nephrotic syndrome and the like. Triptolide main pharmacological effects include: anti-inflammatory, anti-tumor, immune suppression, recent studies have shown that triptolide has a protective effect on cardiovascular disease and osteoporosis. Based on the recent research progress of triptolide, this article reviews the pharmacological effects of triptolide.